Biomicroscopic findings cannot always give all the information needed to distinguish KC from related ectatic corneal conditions. In severe cases, the extended area of corneal thinning also complicates the differentiation. In early cases, however, the differential diagnosis may be more challenging since the cornea may look relatively normal. In moderate cases of KC, the differentiation is typically possible based on slit-lamp examination and corneal tomography with evaluation of the location of the corneal thinning region. The most relevant corneal pathologies that may imitate the tomographic KC pattern are Pellucid Marginal Degeneration (PMD), Keratoglobus, Posterior Keratoconus and Fuchs Terrien’s Marginal Degeneration (FTMD). FINANCIAL DISCLOSURE: No author has a financial or proprietary interest in any material or method mentioned.ĭistinguishing Keratoconus (KC) from other corneal ectatic diseases and thinning disorders is essential for a stage-appropriate and suitable management of each condition. Asphericity and Avg NT((D))/IS((D)) were clinically relevant in discriminating PMD from other groups. CONCLUSIONS: The PMD index appeared to be highly sensitive and specific for diagnosing PMD. The PMD index (AROC curve, 0.935), with a cutoff of 3.45 or higher had 90% sensitivity and 93.7% specificity to distinguish PMD from keratoconus and had 100% sensitivity and 100% specificity to distinguish PMD from control eyes, with a cutoff of 2.46 or higher (AROC curve, 1.000). The highest area under the receiver-operating-characteristic (AROC) curve in discriminating PMD from keratoconus was for asphericity (0.974 cutoff ≥-0.07 sensitivity 93.3% specificity 90.6%) followed by the ratio of average power values of the nasal and temporal quadrants to the average power values of the inferior and superior quadrants (Avg NT((D))/IS((D))) (0.959 cutoff ≥1.005 sensitivity 96.7% specificity 90.6%). RESULTS: Of the indices, the mean values of anterior elevation (AE), ratio of the AE to the anterior best-fit sphere, ratio of the average power values of nasal quadrant to the average power values of inferior quadrant, and difference between maximum keratometry (K) and minimum K were significantly different between the 3 groups (P<.05). These values were analyzed and compared between PMD patients, keratoconus patients, and control subjects. METHODS: Anterior and posterior corneal elevations and thickness indices were obtained from the Orbscan IIz topographer. DESIGN: Initial model-building retrospective study. SETTING: LV Prasad Eye Institute, Hyderabad, India. Eckler's has what you need to make your Corvette shine in any crowd.PURPOSE: To determine and compare corneal elevation and thickness indices, thereby formulating a reliable index to distinguish eyes with pellucid marginal degeneration (PMD) from keratoconus eyes and normal (control) eyes. POR-15 is a worthwhile investment for any restoration. Glisten PC is unaffected by most common chemicals, salt, acids, alkalis, and fertilizers, making it extremely useful in defense against corrosive material-even graffiti! A solvent-soaked rag will wipe away graffiti without damage to your valued possession. POR-15 Glisten PC can be sprayed or brushed to protect wheels, bumpers, polished aluminum, chrome, brass, stainless steel, and existing paint without cracking, chipping, or yellowing. Glisten PC utilizes high-solid, moisture-curing urethane technology to provide excellent adhesion, corrosion protection, flexibility, and UV stability, with tensile strength two to three times higher than other clear coats. "All that glistens is not gold." How true, but POR-15 Glisten PC, with its high-gloss, rock-hard, water-clear finish is definitely worth its weight in gold. Comes In 1 Quart Can, Hardener Included.Tensile Strength Two To Three Times Higher Than Other Clear Coats.Provides Corrosion Protection, Flexibility, And UV Stability.High-Gloss Water-Clear Finish With Excellent Adhesion For All Metals.
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